Some Developmental Analogies

between the autonomous human placenta and the global microbiome.
  • Both systems have highly integrated and extremely complex metabolisms.

  • Both systems are systemically coupled to other systems, yet demonstrate distinct autonomy.

  • Both systems control the homeostatic regulation of it's internal environment through homeorhetic circuits.

  • Both systems display a powerful biological imperative.

  • Hypoxia stimulates stem cell proliferation in both systems.

  • Both cellular organizations individuate in a steep positive gradient of oxygen tension.

  • Both systems have a first trimester exponential growth rate, followed by a slow to ceasing growth rate.